What are processing bodies (P bodies), and what role do they play in mRNA regulation?

Question

Accepted Answer

Hello everyone welcome back. Here's our next problem. It says all of the following are functions of processing bodies or peabodys and M. RNA regulation. Except so we're gonna think about peabodys and their functions and regulating M. R. N. A. Translation. Knowing that we are looking for the answer choice. That is not a function of peabody's. So with that in mind let's recall what these are and what they do from our content video. Just going to paste up a little description here. So peabody's are those Granules found in the cell cytoplasm. They have the characteristic of liquid droplets and they are made up of non translated M. RNA. And proteins associated with M. RNA decay processes highlight that non trans AM RNA and proteins associated with M. RNA decay processes. So how they get involved in the regulation is that they degrade M. R. N. A. That's not going to be translated, preventing silencing or down regulating its gene expression. So they contain things like Exxon nucleus is which remove nucleotides one by one from the end of a poly nucleotide chain. De capping enzymes. They remove that cap that stabilizes them. RNA. RNA healing cases and more proteins involved in the storage and destruction of M. R. N. A. So that's essential for post transcription gene regulation because they degrade the M. RNA transcript that otherwise would be translated into a protein. So when we look at our answer choices we look at choice A. And we see right away M. RNA spicing spicing is done in the nucleus that's done to create the mature M. RNA that is acted upon by the peabodys which we know are in the cytoplasm we saw here they were in the cell cytoplasm. So the peabodys begin to degrade those M. R. N. A. S. After the M. RNA has been spliced in the nucleus. So this is our correct answer. M RNA splicing. That is not a function of the peabodys because that occurs before the M. R. Mature M. R. N. A transcript travels into the sell side of plaza. So again, we already have a correct answer. But to be thorough, let's go through the others. Choice B is M RNA translation. We know that is a function as the peabodys hang on to M. R. N. A. S. That are not to be translated and degrade them preventing M. RNA translation. So that's not our answer as um getting involved in that is a function. Choice C. M. RNA storage. We see directly that these peabody's are involved in the storage of non translated M. RNA S. Since that is a function of the peabodys, that's not our answer choice. And then finally choice D. M. RNA degradation. And yes, the peabodys are very involved containing all these enzymes involved in M. RNA degradation to prevent its translation. But since that's a function of peabody's that's not our answer choice. So again, all the following are functions of processing bodies. Peabody's in M. RNA regulation except choice A. M. RNA splicing. See you in the next video

What are processing bodies (P bodies), and what role do they play in mRNA regulation?

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Key Concepts

Processing Bodies (P Bodies)

mRNA Regulation

Role of P Bodies in mRNA Decay and Storage