For courses in biochemistry.

Engage students in biochemistry visually and through real-world applications

Biochemistry: Concepts and Connections engages students with a unique approach to visualization, synthesis of complex topics, and connections to the real world. The author team builds quantitative reasoning skills and provides students with a rich, chemical perspective on biological processes. The text emphasizes fundamental concepts and connections, showing how biochemistry relates to practical applications in medicine, agricultural sciences, environmental sciences, and forensics.

The newly revised 2nd Edition integrates even more robust biochemistry-specific content in Mastering^TM Chemistry, creating an interactive experience for today’s students. New Threshold Concept Tutorials help students master the most challenging and critical ideas in biochemistry, while Interactive Case Studies connect course material to the real world by having students explore actual scientific data from primary literature.

Key features

• All art was created by medical illustrators and reviewed by a faculty advisory board made up of members of VIBE (Visualization in Biochemistry Education) Research Group to ensure that all visuals are beautifully accurate and pedagogically sound.
• The concise presentation and organisational choices of the text result from the combined classroom experience of the renowned author team, providing students with a resource they will use during the course and a solid reference for their futures:
• Each chapter builds upon student understanding of fundamentals, presenting the theme of structure and function and covering only the content that students actually need.
• The first several chapters introduce biochemistry as a quantitative science with Chapters 2 and 3 focusing on water, the matrix of life, and bioenergetics. Subsequent chapters present structure and function of biological molecules, followed by intermediary metabolism, and then genetic biochemistry.
• The text presents the principles of biochemical techniques throughout as well as many, diverse real-world applications.

New to this edition

• The groundbreaking visual narrative highlights and reinforces overarching themes (chemical logic, regulation, interface between chemistry and biology) using a wide range of graphic representations, from macromolecules to cellular structures as well as reaction mechanisms and metabolic pathways. Students see and grasp the bigger picture and further their understanding of the material including the mapping of bioenergetic calculations to three-dimensional structures, precise reference charts that highlight chemical interrelationships, integrated text explanations, and detailed molecular models.
• Two New Foundation Figures bring the total in the text to 10. Foundation Figures integrate core chemical and biological connections visually, providing a way to organise highly complex and detailed material and making biochemistry more manageable, understandable, and easier to synthesise. Existing Foundation Figures were reviewed by a learning science team and honed to be more pedagogically effective. Foundation Figures include dedicated questions to be used in class via Learning Catalytics or can be assigned in Mastering as stepwise animations with follow-up assessment.
• Enhanced connection between complex multi-step art pieces and the related in-text discussion by adding colour-coded step callouts (from the art) to the in-text discussion. This allows students to more easily connect the details in the text to the art.
• Tools of Biochemistry highlight the most important research techniques and emphasise biochemistry as an experimental science by including 16 separate sections of cutting edge references. These end-of-chapter references (about twelve per chapter) include links to Nobel Prize lectures for example.
• Concept and Connection statements highlighted in the narrative call students' attention to fundamental concepts as well as their real-world applications and demonstrate how individual topics are related.
• End-of-chapter problems bring the total per chapter to 15-25 and often include real-world applications.. Approximately half of the problems have brief answers at the end of the book, with complete answers provided in a separate solutions manual.