
Concepts of Genetics, 13th edition
- William S Klug |
- Michael A Palladino |
- Darrell Killian |
Title overview
For all introductory genetics courses.
Core concepts with a focus on problem solving and ethics
Concepts of Genetics covers the fundamental ideas of genetics while exploring modern techniques and applications of genetic analysis. It offers digestible explanations of complex, analytical topics and aims to equip students to become effective problem solvers.
The 13th Edition has been updated to cover cutting-edge genetics content such as the first-ever gene therapy using genome-editing technology, the use of artificial intelligence in bioinformatical analysis, advances in the field of synthetic biology, and the latest research on human genomic diversity. It includes a new Special Topics Chapter on genetic testing, enhanced coverage on gene-edited food, and significant updates on genetic techniques and genomic analyses. A new Extra Spicy Question appears in each chapter to bolster the emphasis on problem solving. Additionally, significant revisions embrace diversity and offer an inclusive pedagogical approach to genetics.
Hallmark features of this title
- Problem solving and analytical thinking skills are emphasized and optimized through a suite of features in every chapter:
- Now Solve This Problems test student knowledge; a hint and a brief answer are provided in the appendix.
- Insights and Solutions feature in each Problems and Discussion Questions section poses problems or questions, and provides detailed solutions and analytical insights as answers are provided. A Concept Question in the Problems and Discussion Questions asks the student to review and comment on common aspects of the Key Concepts listed at the beginning of each chapter.
- How Do We Know? Questions ask students to identify the experimental basis underlying important concepts and conclusions: i.e., how we know what we know.
- Evolving Concept of the Gene is a short feature in appropriate chapters that introduces a rich history of genetics, highlighting how scientists' understanding of what a gene is has changed over time.
- Exploring Genomics boxes help students apply genetics to modern techniques such as genomics, bioinformatics and proteomics.
New and updated features of this title
- NEW: Genetic testing is explored in a dedicated Special Topics in Modern Genetics chapter, one of several specialized chapters that provide unique, cohesive coverage of selected topics.
- NEW: A “New and Challenging” problem in each Extra-Spicy Problems section engages students in published research studies and ask them to think analytically about new concepts, experimental strategies and data sets.
- REVISED: Expanded Figure Walkthroughs take key figures from the text and bring them to life with animation and narration.
- NEW/REVISED: Updated content and topics throughout include updated coverage of gene-editing using CRISPR-Cas and its potential in genetic technology (Ch. 1), new coverage on mtDNA gene editing (Ch. 9), new coverage of synthetic biology and the engineering of codons to specify non-traditional amino acids (Ch. 14), new coverage of genetic testing (ST. 3), new content on genetic technology and food (ST. 4), AI and its applications in bioinformatics (Ch. 21), and much more.
- REVISED: Updated research and data are incorporated throughout, with extensive revisions made to promote an inclusive approach to teaching and learning.
Key features
Features of Mastering Genetics for the 13th Edition
- NEW: Interactive Reading Assignments allow students to read, watch and practice in one seamless, integrated experience. Assign specific sections of the eTextbook along with auto-gradable Mastering questions and activities, Dynamic Study Modules, and more.
- Prebuilt Interactive Reading Assignments can be used as-is to help faculty efficiently create assignments; or, they can be customized to include your own videos, questions and more. You can also build your own Interactive Reading Assignments from scratch. They are assignable and auto-graded as homework in Mastering Genetics; Gradebook analytics track progress and provide data for instructors and students.
- NEW: AI-powered study tool for Mastering is an intuitive study companion that draws from trusted Pearson content to help students perform successfully on the questions and activities you’ve assigned in your course.
- REVISED: Dynamic Study Modules are interactive flashcards offering multiple sets of questions with extensive feedback so students can test, learn, and retest until they master the material. These can be assigned for credit or used for self-study, and they are powerful pre-class activities that help prepare students for more involved content coverage or problem solving in class.
- REVISED: Expanded Figure Walkthroughs take key figures from the text and bring them to life with animation and narration. They are assignable through Mastering Genetics with related assessments.
- NEW: Added tutorials on topics like CRISPR-Cas will help students master important, challenging concepts. New experimental, data-based tutorials engage students in published research studies and ask them to think analytically about new concepts, experimental strategies and data sets.
Features of Pearson+ eTextbook for the 13th Edition
- NEW: AI-powered study tool for Pearson+ eTextbook is an intuitive, 24/7 study companion that draws from vetted Pearson content to keep students engaged with the book you’ve chosen for your course. For example, students can ask the study tool for summaries, explanations of challenging concepts or practice questions to test their understanding.
Table of contents
I: Genes, Chromosomes, and Heredity
- 1: Introduction to Genetics
- 2: Mitosis and Meiosis
- 3: Mendelian Genetics
- 4: Extensions of Mendelian Genetics
- 5: Chromosome Mapping in Eukaryotes
- 6: Genetic Analysis and Mapping in Bacteria and Bacteriophages
- 7: Sex Determination and Sex Chromosomes
- 8: Chromosomal Mutations: Variation in Number and Arrangement
- 9: Extranuclear Inheritance
II: DNA: Structure, Replication, and Organization
- 10: DNA Structure and Analysis
- 11: DNA Replication and Recombination
- 12: DNA Organization in Chromosomes
III: Gene Expression and its Regulation
- 13: The Genetic Code and Transcription
- 14: Translation and Proteins
- 15: Gene Mutation, DNA Repair, and Transposition
- 16: Regulation of Gene Expression in Bacteria
- 17: Transcriptional Regulation in Eukaryotes
- 18: Posttranscriptional Regulation in Eukaryotes
- 19: Epigenetic Regulation of Gene Expression
IV: Genetic Technology and Genomics
- 20: Recombinant DNA Technology
- 21: Genomic Analysis
- 22: Applications of Recombinant DNA Technology and Genomics
V: Genetic Analysis of Organisms and Populations
- 23: Developmental Genetics
- 24: Cancer Genetics
- 25: Quantitative Genetics and Multifactorial Traits
- 26: Population and Evolutionary Genetics
Special Topics in Modern Genetics
- ST 1: CRISPR-Cas and Genome Editing
- ST 2: DNA Forensics
- ST 3: Genetic Testing
- ST 4: Genetic Technology and Food
- ST 5: Gene Therapy
- ST 6: Advances in Neurogenetics: The Study of Huntington Disease
Author bios
About our authors
William S. Klug is an Emeritus Professor of Biology at The College of New Jersey (formerly Trenton State College) in Ewing, New Jersey, where he served as Chair of the Biology Department for 17 years. He received his B.A. degree in Biology from Wabash College in Crawfordsville, Indiana, and his Ph.D. from Northwestern University in Evanston, Illinois. Prior to The College of New Jersey, he was on the faculty of Wabash College as an Assistant Professor, where he first taught genetics as well as general biology and electron microscopy.
His research interests have involved ultrastructural and molecular genetic studies of development, utilizing oogenesis in Drosophila as a model system. He has taught the genetics course and the senior capstone seminar course in Human and Molecular Genetics to undergraduate biology majors for over 4 decades. He was the recipient in 2001 of the first annual teaching award given at The College of New Jersey, granted to the faculty member who most challenges students to achieve high standards. He also received the 2004 Outstanding Professor Award from Sigma Pi International; that same year he was nominated as Educator of the Year, an award given by the Research and Development Council of New Jersey. When he is away from revision files and reading the genetic literature, he can often be found paddling in the Gulf of Mexico or in Maine's Penobscot Bay.
Michael A. Palladino is currently Provost and Vice President for Academic Affairs at Stockton University. He is the former Vice Chancellor for Academic Affairs at Bloomfield College of Montclair State University. Prior to Bloomfield, he served as Vice Provost for Graduate Studies, Dean of the School of Science, and Professor of Biology at Monmouth University. He received his B.S. in biology from Trenton State College (now The College of New Jersey), where he was a student and advisee of Steve Klug, and his Ph.D. in Anatomy and Cell Biology from the University of Virginia.
He has received several awards for research, teaching, and leadership including the 2023 Distinguished Service Award and the 2009 Young Andrologist Award of the American Society of Andrology, the 2005 Distinguished Teacher Award from Monmouth University, and the 2005 Caring Heart Award from the New Jersey Association for Biomedical Research.
Darrell J. Killian is an Associate Professor in the Department of Molecular Biology at Colorado College in Colorado Springs, CO, where he has served as department chair. He received his B.A. degree in Molecular Biology and Biochemistry from Wesleyan University in Middletown, Connecticut, prior to working as a Research Technician In Molecular Genetics at Rockefeller University in New York, New York. He earned his Ph.D. in Developmental Genetics from New York University in New York, New York and received his postdoctoral training at the University of Colorado - Boulder in the Department of Molecular, Cellular, and Developmental Biology.
Prior to joining Colorado College, he was an Assistant Professor of Biology at the College of New Jersey in Ewing, New Jersey, where he first met Dr. Klug. His research focuses on the genetic regulation of animal development, and he has received funding from the National Institutes of Health and the National Science Foundation. Currently, he and his undergraduate research assistants are investigating the molecular genetic regulation of nervous system development using C. elegans and Drosophila as model systems. He teaches undergraduate courses in genetics, molecular and cellular biology, stem cell biology, and developmental neurobiology. When away from the classroom and lab, he can often be found watching his daughters play soccer, playing frisbee with his dog, or cycling trails.