Genetic Analysis, 4th edition
- Mark F. Sanders |
- John L. Bowman |
Title overview
For all introductory genetics courses.
Convey the dynamism of genetics
Genetic Analysis: An Integrated Approach contextualizes 3 core challenges of learning genetics: solving problems, understanding the links between traditional genetics models and more modern approaches, and understanding evolution. Problem solving is incorporated throughout, rather than set only at the end of chapters,
The 4th Edition is substantially revised and expands the authors’ proven framework into visual literacy. It adds 3 new Application Chapters, covers new topics such as uses of modified CRISPR, molecular genetic evolution and molecular population genetics, and many more enhancements.
Hallmark features of this title
- Genetic Analysis worked examples guide students using a consistent 3-step approach of Evaluate, Deduce, and Solve problems.
- Break It Down prompts in worked examples help students formulate an approach to solving a problem by breaking down essential information.
- Case Studies are real-world examples that highlight chapter concepts and show practical applications of genetics.
- Foundation Figures combine visuals and words in a concise, easily followed format to help students grasp pivotal concepts.
- Visualizing Genetics features take a systematic approach to the understanding of visual material
- Caption Queries for most figures are follow-on questions linked directly to textbook figures, designed to elicit responses based on close examination and understanding of the information presented.
New and updated features of this title
- New and updated Application Chapters:
- 3 new Application Chapters cover gene therapy and gene editing applications in humans, plants, and animals (Ch. G); bioethics (Ch. H); and the origin, analysis, evolution, and potential cure of sickle cell disease (Ch. F). The 5 retained Application Chapters have been updated.
- Fully revised chapters 13-16 covering the regulation of eukaryotic gene expression, the analysis of gene function, recombinant DNA, and genomics are almost entirely rewritten and updated for currency.
- New and expanded discussion of the molecular genetics of all 7 of Mendel’s traits, including discussion of Mendel’s data relative to expected experimental outcomes and to potential genetic linkage.
- Expanded topic coverage includes molecular genetic evolution and molecular population genetics, and the uses of modified CRISPR to precisely edit genomes and regulate gene expression.
- Expanded context of human evolution is updated with expanding genomic data from extant and ancient humans.
Key features
Features of Mastering Genetics for the 4th Edition
- Tutorials on topics like CRISPR–Cas help students master important and challenging concepts.
- Dynamic Study Modules are interactive flashcards that present multiple sets of questions and provide extensive feedback so students can test, learn, and retest until they achieve mastery of the textbook material.
- Practice Problems, similar to end-of-chapter questions in scope and level of difficulty, are found only in Mastering Genetics.
- Solutions are not available in the Study Guide and Solutions Manual, and the question bank extends instructors' options for assigning challenging problems.
- Each problem includes specific wrong-answer feedback to help students learn from their mistakes and to guide them toward the correct answer.
- Nearly 90% of the text’s end-of-chapter questions are included in the item library; question types include multiple-choice, sorting, labeling, numerical, and ranking.
Features of Pearson+ eTextbook for the 4th Edition
- 5 new Visualizing Genetics Videos present walkthroughs of key figures and tables, bringing them to life with animation and narration. They prompt students to:
- Evaluate: identify the type of image, describe what the figure is illustrating or presenting, and determine any conventions present
- Connect: connect the information in an image with information in the text and other figures
- Assess: describe and identify the information contained in the image.
- Interpret: determine the meaning of the image information and identify conclusions drawn from the image content.
Table of contents
- 1: The Molecular Basis of Heredity, Variation, and Evolution
- 2: Transmission Genetics
- 3: Cell Division and Chromosome Heredity
- 4: Gene Interaction
- 5: Genetic Linkage and Mapping in Eukaryotes
- 6: Genetic Analysis and Mapping in Bacteria and Bacteriophages
- Application A: Human Hereditary Disease and Genetic Counseling
- 7: DNA Structure and Replication
- 8: Molecular Biology of Transcription and RNA Processing
- 9: The Molecular Biology of Translation
- Application B: Human Genetic Screening
- 10: Eukaryotic Chromosome Abnormalities and Molecular Organization
- 11: Gene Mutation, DNA Repair, and Homologous Recombination
- 12: Regulation of Gene Expression in Bacteria and Bacteriophage
- 13: Regulation of Gene Expression in Eukaryotes
- 14: Analysis of Gene Function by Forward Genetics and Reverse Genetics
- Application C: The Genetics of Cancer
- 15: Recombinant DNA Technology
- 16: Genomics: Genetics from a Whole-Genome Perspective
- 17: Organellar Inheritance and the Evolution of Organellar Genomes
- 18: Developmental Genetics
- 19: Genetic Analysis of Quantitative Traits
- 20: Population Genetics and Evolution at the Population, Species, and Molecular Levels
- Application D: Human Evolutionary Genetics
- Application E: Forensic Genetics
- Application F: Sickle Cell Disease: Origin, Evolution, Analysis and Cure
- Application G: Gene Therapy and Gene Editing Applications in Humans, Plants, and Animals
- Application H: Bioethics in the Genome Age
- Useful References
- Appendix: Answers
- Credits
- Math and Chemistry-Based Glossary
- Glossary
Author bios
About our authors
Mark F. Sanders has been a faculty member in the Department of Molecular and Cellular Biology at the University of California, Davis, since 1985. Now Lecturer Emeritus, he has taught more than 150 genetics courses to nearly 35,000 undergraduate students. Although he specializes in teaching the genetics course for which this book is written, his genetics teaching experience also includes a genetics laboratory course, an advanced human genetics course for biology majors, and a human heredity course for nonscience majors, as well as introductory biology and courses in population genetics and evolution. He has also served as an advisor to undergraduate students and in undergraduate education administration, and he has directed several undergraduate education programs.
Dr. Sanders received his B.A. degree in Anthropology from San Francisco State University, his M.A. and Ph.D. degrees in Biological Anthropology from the University of California, Los Angeles, and 4 years of training as a postdoctoral researcher studying inherited susceptibility to human breast and ovarian cancer at the University of California, Berkeley.
John L. Bowman is a professor in the School of Biological Sciences at Monash University in Melbourne, Australia. He received a B.S. in Biochemistry at the University of Illinois at Urbana-Champaign in 1986 and a Ph.D. in Biology from the California Institute of Technology in Pasadena, California. His Ph.D. research focused on how the identities of floral organs are specified in Arabidopsis (described in Chapter 18), and he conducted postdoctoral research at Monash University on the regulation of floral development. From 1996 to 2006, his laboratory at UC Davis investigated the developmental genetics of plants, focusing on how leaves are patterned. From 2006 to the present, he has been a professor at Monash University where his laboratory studies land plant evolution using a developmental genetics approach. He was elected a Fellow of the Australian Academy of Science in 2014. At UC Davis, he taught genetics “from Mendel to cancer” to undergraduate students; he continues to teach genetics courses at Monash University, incorporating evolutionary thinking whenever possible.