During mitosis, during which phase do chromosomes line up in the middle of the cell (at the metaphase plate)?

• A. Metaphase
• B. Telophase
• C. Anaphase
• D. Prophase

Answer: (A)

Verified step by step guidance

1. Understand the sequence of phases in mitosis: Prophase, Metaphase, Anaphase, and Telophase.
2. Recall that during Prophase, chromosomes condense and the mitotic spindle begins to form, but chromosomes are not yet aligned.
3. Identify that Metaphase is the phase where chromosomes align at the cell's equatorial plane, known as the metaphase plate.
4. Recognize that during Anaphase, sister chromatids separate and move toward opposite poles of the cell.
5. Note that Telophase involves the reformation of the nuclear envelope around the separated chromatids, now at opposite poles.