Match the following protein structures with their appropriate ...

Question

Match the following protein structures with their appropriate definitions

i. Primary Structure _____________
ii. Secondary Structure _____________
iii. Tertiary Structure _____________
iv. Quaternary Structure _____________

a. 3D conformation of a single polypeptide chain

b. Linear sequence of amino acids

c. Folding of multiple polypeptide chains together

d. Local structures of a single polypeptide chain

Accepted Answer

Okay, everyone match the following protein structures with their appropriate definitions. Okay, so great practice question going over all the different structures within a protein that we learn. So primary, secondary, tertiary, excuse me, tertiary and quaternary structure. So we have to remember the main differences between these different structures within a protein. So remember primary structure is going to be the first structure. So what do we know about primary structure? Remember that it's going to be a string of amino acids attached to one another like this. And they're going to be attached in a particular order. So these are all amino acids. And they're going to have a unique order, a unique arrangement that creates a protein. So primary structure is going to be answer choice B. A linear sequence of amino acids. So we're gonna put B and cross that one out. Okay. So now that we have our linear sequence of amino acids in a particular order, what is secondary structure going to entail? Well, remember that that linear sequence of amino acids is going to form some structures within it. And those are gonna be things like alpha helices. And, beta pleated sheets. And these are going to be part of the secondary structure. They're going to form from the sequence of amino acids. So these are going to be local structures. Let's see. Wait. Which one did I Sorry. Yes. Local structures of a single polypeptide chain. That is d. So, that is this one. So, the local structures in a single polypeptide chain like alpha helices and beta pleated sheets. So, we're gonna cross this one out. So now we have 2 left. Let's do tertiary structure. So now that we have our amino acid sequence that has these small structures in it like alpha helices and beta pleated sheets. What do we do next? We need to fold that polypeptide. So we need some folding happening here in this single polypeptide. So that means that answer choice A, the 3 d conformation of a single polypeptide chain is going to go for tertiary structure. The reason this is the correct answer, remember tertiary structure is only referring to a single polypeptide chain, not multiple polypeptide chains. So the 3 d folding conformation of a single polypeptide chain. Now, finally, we have quaternary structure. Remember, we learned that quaternary structure only applies to proteins that have multiple polypeptide chains. So answer choice c is the correct answer because it says folding of multiple polypeptide chains together, and this is going to create a multi meric protein, a protein composed of multiple polypeptide chains. If the protein is only composed of 1 polypeptide chain, you're only gonna have primary, secondary, and tertiary structure. However, if the protein is composed of more than 1 polypeptide chain, you will also have quaternary structure, and quaternary structure is gonna be dealing with how those different polypeptide chains interact with one another to create 1 protein complex. Okay, everyone. Let's go on to our next Topic.

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