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Ch. 4 - Extensions of Mendelian Genetics
Klug - Concepts of Genetics  12th Edition
Klug12th EditionConcepts of Genetics ISBN: 9780135564776Not the one you use?Change textbook
Chapter 4, Problem 21a

In a unique species of plants, flowers may be yellow, blue, red, or mauve. All colors may be true breeding. If plants with blue flowers are crossed with red-flowered plants, all F₁ plants have yellow flowers. When these produced an F₂ generation, the following ratio was observed:
9/16 yellow: 3/16 blue: 3/16 red: 1/16 mauve
In still another cross using true-breeding parents, yellow-flowered plants are crossed with mauve-flowered plants. Again, all F₁ plants had yellow flowers, and the F₂ showed a 9:3:3:1 ratio, as just shown.
Describe the inheritance of flower color by defining gene symbols and designating which genotypes give rise to each of the four phenotypes.

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Define the gene symbols: Assign two genes, A and B, to control flower color. Each gene has two alleles: A (dominant) and a (recessive), and B (dominant) and b (recessive).
Determine the phenotypes based on genotypes: From the F₂ ratio (9:3:3:1), this is a classic dihybrid cross pattern. Assign phenotypes to genotypes as follows: A-B- (yellow), A-bb (blue), aaB- (red), and aabb (mauve).
Explain the F₁ generation: When blue (A-bb) is crossed with red (aaB-), the F₁ generation is heterozygous for both genes (AaBb), resulting in yellow flowers due to the dominance of A and B alleles.
Analyze the F₂ generation: The F₂ generation results from a dihybrid cross (AaBb x AaBb), producing a 9:3:3:1 phenotypic ratio. This confirms the inheritance pattern and the genotypic assignments for each phenotype.
Describe the second cross: When yellow (A-B-) is crossed with mauve (aabb), the F₁ generation is again heterozygous (AaBb) and yellow due to dominance. The F₂ generation from this cross also shows the 9:3:3:1 ratio, further supporting the genetic model.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Mendelian Inheritance

Mendelian inheritance refers to the principles of heredity established by Gregor Mendel, which describe how traits are passed from parents to offspring through discrete units called genes. In this context, traits such as flower color are determined by alleles, which can be dominant or recessive. Understanding these principles is crucial for predicting the outcomes of genetic crosses, such as the F₁ and F₂ generations mentioned in the question.
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Phenotypic Ratios

Phenotypic ratios represent the relative frequencies of different observable traits in the offspring resulting from a genetic cross. The 9:3:3:1 ratio observed in the F₂ generation indicates a dihybrid cross involving two traits, where the dominant traits mask the recessive ones. This ratio helps in understanding the inheritance patterns and the expected distribution of phenotypes based on the genotypes of the parents.
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Genotype and Alleles

Genotype refers to the genetic constitution of an organism, specifically the alleles it possesses for a given trait. In this case, flower color is influenced by different alleles, which can be represented by symbols (e.g., Y for yellow, B for blue, R for red, and M for mauve). Identifying the genotypes that correspond to each phenotype is essential for accurately describing the inheritance patterns and predicting the outcomes of future crosses.
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Related Practice
Textbook Question

In a species of the cat family, eye color can be gray, blue, green, or brown, and each trait is true breeding. In separate crosses involving homozygous parents, the following data were obtained:

In a cross between a gray-eyed cat and one of unknown genotype and phenotype, the F₁ generation was not observed. However, the F₂ resulted in the same F₂ ratio as in cross C. Determine the genotypes and phenotypes of the unknown P₁ and F₁ cats.

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Textbook Question

In a plant, a tall variety was crossed with a dwarf variety. All F₁ plants were tall. When F₁xF₁ plants were interbred, 9/16 of the F₂ were tall and 7/16 were dwarf. Explain the inheritance of height by indicating the number of gene pairs involved and by designating which genotypes yield tall and which yield dwarf. (Use dashes where appropriate.)

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Textbook Question

In a plant, a tall variety was crossed with a dwarf variety. All F₁ plants were tall. When F₁xF₁ plants were interbred, 9/16 of the F₂ were tall and 7/16 were dwarf. What proportion of the F₂ plants will be true breeding if self-fertilized? List these genotypes.

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Textbook Question

In a unique species of plants, flowers may be yellow, blue, red, or mauve. All colors may be true breeding. If plants with blue flowers are crossed with red-flowered plants, all F₁ plants have yellow flowers. When these produced an F₂ generation, the following ratio was observed:

9/16 yellow: 3/16 blue: 3/16 red: 1/16 mauve

In still another cross using true-breeding parents, yellow-flowered plants are crossed with mauve-flowered plants. Again, all F₁ plants had yellow flowers, and the F₂ showed a 9:3:3:1 ratio, as just shown. Determine the F₁ and F₂ results of a cross between true-breeding red and true-breeding mauve-flowered plants.

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Textbook Question

Five human matings (1–5), identified by both maternal and paternal phenotypes for ABO and MN blood-group antigen status, are shown on the left side of the following table:

Each mating resulted in one of the five offspring shown in the right-hand column (a–e). Match each offspring with one correct set of parents, using each parental set only once. Is there more than one set of correct answers?

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Textbook Question

A husband and wife have normal vision, although both of their fathers are red–green color-blind, an inherited X-linked recessive condition. What is the probability that their first child will be (a) a normal son, (b) a normal daughter, (c) a color-blind son, (d) a color-blind daughter?

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