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Ch. 15 - Innate Immunity
Bauman - Microbiology with Diseases by Taxonomy 6th Edition
Bauman6th EditionMicrobiology with Diseases by TaxonomyISBN: 9780134832302Not the one you use?Change textbook
Chapter 15, Problem 1

Phagocytes of the epidermis are called:
a. Microglia
b. Goblet cells
c. Alveolar macrophages
d. Dendritic cells

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1
Understand that phagocytes are immune cells that engulf and digest pathogens and debris.
Recall that the epidermis is the outermost layer of the skin, which contains specialized immune cells.
Identify the types of phagocytes listed: Microglia are found in the central nervous system, Goblet cells secrete mucus and are not phagocytes, Alveolar macrophages are found in the lungs.
Recognize that dendritic cells are phagocytic cells located in the epidermis and act as antigen-presenting cells to initiate immune responses.
Conclude that the correct answer is dendritic cells, as they are the phagocytes of the epidermis.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Phagocytes

Phagocytes are immune cells that engulf and digest pathogens, debris, and foreign particles. They play a crucial role in the body's innate immune response by identifying and removing harmful microorganisms to protect tissues from infection.
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Epidermal Dendritic Cells (Langerhans Cells)

Dendritic cells in the epidermis, also known as Langerhans cells, are specialized phagocytes that capture antigens and present them to T cells, initiating adaptive immunity. They act as sentinels in the skin, bridging innate and adaptive immune responses.
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Other Phagocytes and Their Locations

Different phagocytes reside in specific tissues: microglia are in the central nervous system, alveolar macrophages in the lungs, and goblet cells produce mucus but are not phagocytes. Recognizing their locations helps identify the correct phagocyte type in a given tissue.
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