Multiple Choice
In a eukaryotic cell, which statement best explains why genomic DNA generally cannot leave the nucleus to be translated in the cytoplasm?
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5. DNA to RNA to Protein
mRNA Export and Nuclear Structures
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Unprocessed mRNA is exported from the nucleus to be processed before translation.
A
True
B
False
Verified step by step guidance1
Understand the process of mRNA synthesis: mRNA is synthesized in the nucleus through transcription, where a DNA template is used to create a pre-mRNA strand.
Recognize the role of pre-mRNA: The initial transcript, known as pre-mRNA, contains both exons (coding regions) and introns (non-coding regions) and requires processing before it can be translated into a protein.
Learn about mRNA processing: Pre-mRNA undergoes several modifications, including 5' capping, 3' polyadenylation, and splicing, where introns are removed and exons are joined together to form mature mRNA.
Identify the location of mRNA processing: All these processing steps occur within the nucleus, ensuring that only mature mRNA is exported to the cytoplasm for translation.
Conclude the statement's accuracy: Since mRNA is processed in the nucleus before being exported, the statement 'Unprocessed mRNA is exported from the nucleus to be processed before translation' is false.
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