What is the total NADH and total FADH 2 produced in one turn of the citric acid cycle?

Hello everyone today. With the following problem. What are the total amounts of N A? DH fa DH two carbon dioxide and A TP or GTP generated th during one complete turn of the creb cycle. So in one complete turn of the TC cycle, there will be three in ad molecules produced. And this is stemming from the conversion of isocitrate the alpha ketoglutarate as well as alpha ketoglutarate to Sueno K A. And then finally malate being converted to oxo acetate. Moreover, one fa DH two molecule is produced and the reaction of succinate to fumarate. Moreover, two molecules of carbon dioxide are yielded first from the reaction of isocitrate to alpha ketoglutarate. And then the second is the reaction from alpha ketoglutarate to SUO K A. And then lastly, there is one A TP or GTP molecule that is yielded from the reaction of succinyl coa to succinate. So if we look at our answer choices, andro choice B best reflects the total amounts of these molecules that are generated overall, I hope this helped. And until next time

Ch.18 Metabolic Pathways and ATP Production

Timberlake - Chemistry: An Introduction to General, Organic, and Biological Chemistry 13th Edition

Timberlake13th EditionChemistry: An Introduction to General, Organic, and Biological ChemistryISBN: 9780134421353Not the one you use?Change textbook

All textbooks

Timberlake 13th Edition

Ch.18 Metabolic Pathways and ATP Production

Problem 40

Chapter 18, Problem 40

What is the total NADH and total FADH₂ produced in one turn of the citric acid cycle?

Verified step by step guidance

Step 1: Understand the citric acid cycle (also known as the Krebs cycle or TCA cycle). It is a series of chemical reactions used by aerobic organisms to generate energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins.

Step 2: Recall that during one turn of the citric acid cycle, specific molecules are produced as intermediates are oxidized. NADH and FADH₂ are generated as electron carriers during these oxidation steps.

Step 3: Identify the steps in the citric acid cycle where NADH is produced. NADH is formed during three specific reactions: (1) the conversion of isocitrate to α-ketoglutarate, (2) the conversion of α-ketoglutarate to succinyl-CoA, and (3) the conversion of malate to oxaloacetate.

Step 4: Identify the step in the citric acid cycle where FADH₂ is produced. FADH₂ is formed during the conversion of succinate to fumarate.

Step 5: Sum up the total NADH and FADH₂ produced in one turn of the cycle. Based on the reactions identified, three NADH molecules and one FADH₂ molecule are produced per turn of the citric acid cycle.

Verified video answer for a similar problem:

This video solution was recommended by our tutors as helpful for the problem above.

Video duration:

Was this helpful?

Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Citric Acid Cycle

The citric acid cycle, also known as the Krebs cycle, is a series of enzymatic reactions that occur in the mitochondria. It plays a crucial role in cellular respiration by oxidizing acetyl-CoA to produce energy carriers. Each turn of the cycle generates high-energy molecules, which are essential for ATP production.

NADH and FADH₂

NADH and FADH₂ are electron carriers produced during the citric acid cycle. NADH is generated from the reduction of NAD⁺, while FADH₂ is produced from the reduction of FAD. These molecules transport electrons to the electron transport chain, where they contribute to ATP synthesis through oxidative phosphorylation.

Energy Yield of the Citric Acid Cycle

In one turn of the citric acid cycle, a total of three NADH and one FADH₂ are produced. This energy yield is critical for understanding the cycle's efficiency in generating ATP. The NADH and FADH₂ produced are then used in the electron transport chain to produce a significant amount of ATP, highlighting the cycle's importance in cellular metabolism.