Multiple Choice
In the context of translation, which organelle is primarily responsible for synthesizing proteins?
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5. DNA to RNA to Protein
Translation
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In eukaryotic translation, what occurs when the ribosome reaches a stop codon (UAA, UAG, or UGA) in the A site?
A
The ribosome shifts reading frames by one nucleotide to bypass the stop codon and continue elongation.
B
A specialized tRNA carrying methionine binds to the stop codon and adds a final amino acid to terminate translation.
C
The large ribosomal subunit alone catalyzes formation of a new peptide bond at the stop codon to cap the polypeptide.
D
A release factor binds in the A site and stimulates hydrolysis of the peptidyl-tRNA bond, releasing the completed polypeptide and leading to ribosome dissociation.
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