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Ch.8 Gases
Timberlake - Chemistry: An Introduction to General, Organic, and Biological Chemistry 13th Edition
Timberlake13th EditionChemistry: An Introduction to General, Organic, and Biological ChemistryISBN: 9780134421353Not the one you use?Change textbook
Chapter 8, Problem 59a

In certain lung ailments such as emphysema, there is a decrease in the ability of oxygen to diffuse into the blood.
a. How would the partial pressure of oxygen in the blood change?

Verified step by step guidance
1
Understand the concept of partial pressure: Partial pressure refers to the pressure exerted by a single gas in a mixture of gases. In the context of blood, the partial pressure of oxygen (PO2) is a measure of the amount of oxygen gas dissolved in the blood.
Recognize the role of diffusion: Oxygen diffuses from the alveoli in the lungs into the blood due to a concentration gradient. This process is driven by the difference in partial pressure between the oxygen in the alveoli and the oxygen in the blood.
Analyze the effect of emphysema: Emphysema damages the alveoli, reducing the surface area available for gas exchange. This impairs the diffusion of oxygen into the blood.
Predict the change in partial pressure: Since less oxygen is able to diffuse into the blood due to the reduced surface area, the partial pressure of oxygen in the blood (PO2) would decrease.
Relate this to the symptoms: A lower partial pressure of oxygen in the blood can lead to hypoxemia, which is a condition characterized by insufficient oxygen levels in the blood, potentially causing symptoms such as shortness of breath and fatigue.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Partial Pressure of Oxygen

Partial pressure of oxygen refers to the pressure exerted by oxygen in a mixture of gases, such as air or blood. It is a crucial factor in determining how oxygen diffuses across membranes, including the alveoli in the lungs. In healthy lungs, oxygen diffuses from areas of higher partial pressure in the alveoli to lower partial pressure in the blood. Understanding this concept is essential for analyzing how lung ailments affect oxygen transport.
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Diffusion

Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the context of the lungs, oxygen diffuses from the alveoli, where its concentration is higher, into the blood, where its concentration is lower. In conditions like emphysema, the surface area for diffusion is reduced, leading to impaired oxygen transfer and affecting the partial pressure of oxygen in the blood.
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Emphysema

Emphysema is a chronic lung condition characterized by the destruction of alveoli, leading to reduced surface area for gas exchange. This damage impairs the lungs' ability to oxygenate blood effectively, resulting in lower partial pressures of oxygen in the bloodstream. Understanding emphysema is vital for comprehending how lung function affects oxygen diffusion and overall respiratory health.