The alternative complement activation pathway involves:
a. Factors B, D, and P
b. The cleavage of C5 to form C9
c. Binding to mannose sugar
d. Recognition of antigens bound to specific antibodies

Question

The alternative complement activation pathway involves:

a. Factors B, D, and P

b. The cleavage of C5 to form C9

c. Binding to mannose sugar

d. Recognition of antigens bound to specific antibodies

Accepted Answer

Hi, everyone. And welcome back. The next problem says, the classical complement activation pathway is initiated by a spontaneous hydrolysis of C three B binding to nano sugar. C recognition of antigens bound to specific antibodies or D the cleavage of C five to form C nine. So recall that when we talk about the actions of the complement system, we have three pathways that converge in a single pathway that will lead to the final cascade and all the activities of the complement system. So first of all, let's eliminate choice d the cleavage of C five to form C nine. When you see those larger numbers C five C nine, we're talking about after our three pathways have converged. So, later on in the process, specifically, we're talking about the part of this process of the formation of the membrane attack complex. So d too late, then our other three choices all involve one of our three activation pathways and the classical pathway. Maybe think we know that the complement system helps antibodies. And when we think about the immune system, antibodies are often kind of the stars of the show of things we think of. First of all. So if we say the classical pathway or you know, the most well known pathway, it's going to involve antibodies and that is choice c recognition of antigens bound to specific antibodies. Now remember the compliment pathway is part of the innate immune system. It isn't recognizing specific pathogens. But what it recognizes is the fact that there's an antibody antigen complex. It doesn't depend on the identity of that antigen. Just the fact that you've got these two together alerts it to the fact, OK, we've got a pathogen, an antibody has bound. It's recognize something. Let's start this complement system. Looking at our other two answer. Choices, choice, a spontaneous hydrolysis of C three. This would be the alternative pathway, not the classical pathway and recall that the alternative pathway begins when you have the compliment protein C three B bound to a microbe. So C three B on my group and C three B is a product of that hydrolysis of C three. So if I say wrong pathway and then choice B binding to nano sugar, this is the lectin pathway, not the classical pathway. So we recall that manos is a sugar commonly found on the outer part cell, outer, you know, outside of the cell of fungi, bacteria and viruses. So it's sort of a warning of like, you know that guy here and in the lectin pathway, lectin binds to nanos on these cells. So, binding to nano sugar is that initiation step of the lectin pathway. So again, our classical complement activation pathway is initiated by choice c recognition of antigens bound to specific antibodies. See you in the next video.

The alternative complement activation pathway involves:
a. Factors B, D, and P
b. The cleavage of C5 to form C9
c. Binding to mannose sugar
d. Recognition of antigens bound to specific antibodies

Verified video answer for a similar problem:

Key Concepts

Alternative Complement Pathway Components

Complement Cascade and C5 Cleavage

Pathway Activation Triggers

The alternative complement activation pathway involves:a. Factors B, D, and Pb. The cleavage of C5 to form C9c. Binding to mannose sugard. Recognition of antigens bound to specific antibodies

Verified video answer for a similar problem:

Key Concepts

Alternative Complement Pathway Components

Complement Cascade and C5 Cleavage

Pathway Activation Triggers

The alternative complement activation pathway involves:
a. Factors B, D, and P
b. The cleavage of C5 to form C9
c. Binding to mannose sugar
d. Recognition of antigens bound to specific antibodies