Indicate which statements are true. Correct all false statements by changing the underlined words.
__________ Wandering macrophages experience diapedesis.

Verified step by step guidance

1. Step 1: Understand the key terms in the statement. 'Wandering macrophages' are a type of white blood cell involved in immune defense, and 'diapedesis' refers to the process by which cells move out of the bloodstream through the walls of capillaries into surrounding tissues.
2. Step 2: Recall that diapedesis is a characteristic behavior of certain white blood cells, such as neutrophils and monocytes, which leave the bloodstream to reach sites of infection or injury.
3. Step 3: Recognize that wandering macrophages are actually macrophages that have already left the bloodstream and reside in tissues; they do not perform diapedesis themselves.
4. Step 4: Identify the correct cell type that undergoes diapedesis. Monocytes, which circulate in the blood, perform diapedesis to enter tissues where they differentiate into macrophages.
5. Step 5: Correct the statement by replacing 'Wandering macrophages' with 'Monocytes' to accurately reflect the cells that experience diapedesis.

Key Concepts

Diapedesis

Diapedesis is the process by which white blood cells, such as macrophages, move out of the bloodstream by squeezing through the endothelial cells of blood vessel walls to reach tissues during inflammation or immune response.

Wandering Macrophages

Wandering macrophages are mobile immune cells derived from monocytes that patrol tissues to detect and engulf pathogens or debris; they are not typically found within blood vessels but migrate through tissues.

Monocytes and Macrophage Differentiation

Monocytes are circulating white blood cells that undergo diapedesis to exit blood vessels and differentiate into macrophages in tissues, which then act as phagocytes to defend against infections.