Which of the following statements is correct?

• A. Under gestational diabetes, the placenta produces hormones that decreases the effectiveness of insulin.  
• B. All forms of diabetes are caused mainly by lifestyle choices. 
• C. Insulin resistance is the major cause for Type I diabetes. 
• D. Type I diabetes is a curable disease that can be totally eliminated through gene therapy. 

Answer: (A)

Verified step by step guidance

1. Understand the context of the question: The problem is asking to identify the correct statement about diabetes, specifically focusing on gestational diabetes, Type I diabetes, and general causes of diabetes.
2. Analyze the first statement: 'Under gestational diabetes, the placenta produces hormones that decrease the effectiveness of insulin.' This is a scientifically accurate statement. During pregnancy, the placenta produces hormones like human placental lactogen, which can lead to insulin resistance, a hallmark of gestational diabetes.
3. Evaluate the second statement: 'All forms of diabetes are caused mainly by lifestyle choices.' This is incorrect because Type I diabetes is an autoimmune condition and not caused by lifestyle factors. Type II diabetes, however, can be influenced by lifestyle choices such as diet and physical activity.
4. Examine the third statement: 'Insulin resistance is the major cause for Type I diabetes.' This is incorrect because Type I diabetes is caused by the immune system attacking insulin-producing beta cells in the pancreas, leading to insufficient insulin production, not insulin resistance.
5. Review the fourth statement: 'Type I diabetes is a curable disease that can be totally eliminated through gene therapy.' This is incorrect because Type I diabetes is currently not curable. While research into gene therapy and other treatments is ongoing, there is no definitive cure at this time.