Human herpesvirus 2 _____.
a. can cause genital herpes
b. may infect a baby at birth
c. causes about 10% of cold sores
d. all of the above

Verified step by step guidance

1. Understand that Human herpesvirus 2 (HHV-2) is commonly known as herpes simplex virus type 2 (HSV-2).
2. Recognize that HSV-2 is primarily associated with genital herpes, which aligns with option a.
3. Consider that HSV-2 can be transmitted from mother to child during childbirth, which supports option b.
4. Acknowledge that while HSV-1 is more commonly associated with cold sores, HSV-2 can also cause them, albeit less frequently, which relates to option c.
5. Conclude that since all the statements (a, b, and c) are true regarding HSV-2, option d, 'all of the above,' is the most comprehensive answer.

Key Concepts

Human Herpesvirus 2 (HHV-2)

Human herpesvirus 2, also known as herpes simplex virus type 2 (HSV-2), is primarily associated with genital herpes. It is a member of the Herpesviridae family and is characterized by its ability to establish lifelong latency in the host's nervous system, leading to recurrent outbreaks of lesions in the genital area.

Transmission and Infection

HHV-2 can be transmitted through direct skin-to-skin contact, particularly during sexual activity. Additionally, it poses a risk of vertical transmission, meaning it can infect a newborn during childbirth if the mother has an active infection, potentially leading to serious health complications for the infant.

Cold Sores and HSV Types

While HSV-1 is primarily responsible for cold sores, HSV-2 can also cause oral herpes, though this is less common. Understanding the distinction between HSV-1 and HSV-2 is crucial, as it informs treatment and prevention strategies, as well as the public's perception of herpes infections.