Indicate whether each statement is true or false. If the statement is false, change the underlined word or phrase to make the statement true.
_____ ABO blood group antigens are found on nucleated cells.
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1
Identify the key terms in the statement: 'ABO blood group antigens' and 'nucleated cells'.
Recall that ABO blood group antigens are specific molecules found on the surface of red blood cells.
Understand that red blood cells are unique in that they do not have a nucleus, unlike most other cells in the body.
Evaluate the statement: Since ABO blood group antigens are found on red blood cells, which are not nucleated, the statement is false.
To correct the statement, replace 'nucleated cells' with 'red blood cells'.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
ABO Blood Group System
The ABO blood group system is a classification of human blood based on the presence or absence of antigens on the surface of red blood cells. There are four main blood types: A, B, AB, and O, determined by the specific antigens present. Understanding this system is crucial for blood transfusions and organ transplants, as incompatible blood types can lead to serious immune reactions.
Antigens are molecules that trigger an immune response, and they can be found on the surface of various cells, including red blood cells, white blood cells, and platelets. In the context of the ABO blood group, the antigens are primarily located on red blood cells, not on nucleated cells. This distinction is important for understanding blood compatibility and the immune system's response to foreign cells.
Nucleated cells are cells that contain a nucleus, which houses the cell's genetic material. Most human cells, except for mature red blood cells, are nucleated. The presence of nucleated cells in the body is significant for various biological processes, but they do not express ABO blood group antigens, which are specific to red blood cells, highlighting the need for accurate identification in blood typing.