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Microbiology

Learn the toughest concepts covered in Microbiology with step-by-step video tutorials and practice problems by world-class tutors.

20. Adaptive Immunity

T Dependent & T Independent Antigens

1

concept

T Dependent & T Independent Antigens

2m

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2

concept

B Cell Activation by T Dependent Antigens

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3

Problem

Which of the following is a step required for activation of a B cell by a T-dependent antigen?

A

The antigen is presented on MHC class I proteins of the T cell.

B

The antigen binds to the BCR of a naive B cell.

C

The antigen is presented on MHC class II proteins of the B cell.

D

TH cell recognizes the antigen as a pathogen and triggers apoptosis in the B cell.

E

TH cell recognizes the antigen as a pathogen and activates the B cell causing the B cell to secrete antibodies.

F

B, C, & E.

G

A, B & E.

4

Problem

T-dependent antigens can stimulate B cells to become activated but require _________ assistance.

A

Interleukin.

B

Cytokine.

C

Interferon.

D

Antibody.

5

concept

B Cell Activation by T Independent Antigens

3m

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6

Problem

T-independent antigens:

A

Interact with MHC I molecules.

B

Require the involvement of T cells.

C

Include pathogen associated polysaccharides.

D

Are usually pathogen associated nucleic acids.

7

Problem

Lipopolysaccharide (LPS) is an endotoxin found on the surface of gram-negative bacteria. LPS can cause the body to enter septic shock and result in multi-system organ failure. Because of its severe effects, it is important that the immune cells react quickly to LPS. LPS is an antigen that can directly trigger antibody secretion once it comes in contact with a B cell. LPS is what kind of antigen?

A

T-independent antigen.

B

Direct antigen.

C

T-dependent antigen.

D

B-independent antigen.

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