One concern that led to the initial passage of federal drug-control legislation in 1906 was:

• A. The development of antibiotics and vaccines
• B. The increase in prescription drug advertising on television
• C. The rise of organized crime related to alcohol prohibition
• D. The widespread sale of mislabeled and adulterated medicines

Answer: (D)

Verified step by step guidance

1. Step 1: Understand the historical context of the 1906 federal drug-control legislation, which is the Pure Food and Drug Act.
2. Step 2: Recognize that this legislation was primarily a response to public health concerns about the safety and labeling of medicines available at the time.
3. Step 3: Identify that the key issue was the widespread sale of medicines that were mislabeled or adulterated, meaning they contained harmful or undisclosed ingredients.
4. Step 4: Note that other options, such as the development of antibiotics, television advertising, or organized crime related to alcohol prohibition, occurred later or are unrelated to the 1906 legislation.
5. Step 5: Conclude that the correct concern leading to the 1906 legislation was the need to regulate the sale of medicines to protect consumers from unsafe and misleading products.