Which of the following sleep aids is generally associated with the least harmful side effects?

• A. Melatonin supplements
• B. Over-the-counter antihistamines
• C. Prescription benzodiazepines
• D. Barbiturates

Answer: (A)

Verified step by step guidance

1. Step 1: Understand the different categories of sleep aids mentioned: melatonin supplements, over-the-counter antihistamines, prescription benzodiazepines, and barbiturates.
2. Step 2: Review the typical side effects and risks associated with each category. For example, benzodiazepines and barbiturates are known for dependency and more severe side effects, while antihistamines can cause drowsiness and other mild effects.
3. Step 3: Recognize that melatonin is a hormone naturally produced by the body to regulate sleep-wake cycles, and supplements generally mimic this natural process with fewer adverse effects.
4. Step 4: Compare the safety profiles of these aids, noting that melatonin supplements tend to have the least harmful side effects compared to the others, which have higher risks of dependency or more serious side effects.
5. Step 5: Conclude that among the options, melatonin supplements are generally considered the safest sleep aid with the least harmful side effects.