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Multiple Choice
In biological theories of depression, the disorder has most consistently been linked to abnormal functioning of which neurotransmitter system?
A
Excess acetylcholine activity
B
Serotonin (5-HT) dysregulation
C
Increased GABAergic transmission
D
Reduced glutamate release across synapses
Verified step by step guidance
1
Step 1: Understand that biological theories of depression focus on the role of neurotransmitters, which are chemical messengers in the brain that influence mood and behavior.
Step 2: Identify the neurotransmitter systems listed in the problem: acetylcholine, serotonin (5-HT), GABA, and glutamate, and recognize their general functions in the brain.
Step 3: Recall that serotonin (5-HT) is widely studied in relation to mood regulation and is often implicated in depression due to its role in emotional processing and mood stabilization.
Step 4: Note that abnormal serotonin functioning, often referred to as serotonin dysregulation, is the most consistently linked neurotransmitter abnormality in depression according to biological theories.
Step 5: Conclude that among the options, serotonin (5-HT) dysregulation best fits the biological theory of depression's focus on neurotransmitter abnormalities.