Which of the following substances can produce symptoms of paranoid psychosis?

• A. Selective serotonin reuptake inhibitors (SSRIs)
• B. Amphetamines
• C. Beta blockers
• D. Acetaminophen

Answer: (B)

Verified step by step guidance

1. Step 1: Understand what paranoid psychosis is — it is a mental state characterized by delusions of persecution or grandeur, often accompanied by hallucinations and severe anxiety.
2. Step 2: Review the pharmacological effects of each substance listed: SSRIs primarily affect serotonin levels and are used to treat depression and anxiety; beta blockers are used to manage cardiovascular conditions and reduce physical symptoms of anxiety; acetaminophen is a pain reliever and fever reducer with no known psychosis-inducing effects.
3. Step 3: Recognize that amphetamines are stimulant drugs that increase the release of dopamine and norepinephrine in the brain, which can lead to heightened alertness, euphoria, but also potential adverse effects such as paranoia and psychosis, especially at high doses or with chronic use.
4. Step 4: Connect the pharmacological action of amphetamines to the symptoms of paranoid psychosis, understanding that excessive dopamine activity is linked to psychotic symptoms.
5. Step 5: Conclude that among the options, amphetamines are the substances most likely to produce symptoms of paranoid psychosis due to their stimulant properties and impact on neurotransmitter systems involved in psychosis.