4. Genetic Mapping and Linkage
Mapping Genes
2:27 minutes
Problem 19b
Textbook Question
Textbook QuestionGenetic linkage mapping for a large number of families identifies 4% recombination between the genes for Rh blood type and elliptocytosis (see Problem 18). At the Rh locus, alleles R and r control Rh+ and Rh- blood types. Allele E producing elliptocytosis is dominant to the wild-type recessive allele e. Tom and Terri each have elliptocytosis, and each is . Tom's mother has elliptocytosis and is Rh- while his father is healthy and has Rh+. Terri's father is Rh+ and has elliptocytosis; Terri's mother is Rh- and is healthy.
What is the probability that the first child of Tom and Terri will be Rh− and have elliptocytosis?
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