Multiple Choice
In the context of DNA replication, what is the primary function of DNA ligase?
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8. DNA Replication
Overview of DNA Replication
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In the overview of DNA replication, what is the primary function of DNA ligase?
A
It seals nicks in the sugar-phosphate backbone by forming phosphodiester bonds, joining Okazaki fragments on the lagging strand.
B
It adds nucleotides to the growing DNA strand in the to direction using the template strand.
C
It synthesizes RNA primers to provide a 3' - O H group for DNA polymerase to extend.
D
It unwinds the parental DNA double helix ahead of the replication fork by breaking hydrogen bonds.
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