During the cell cycle associated with mitosis, in which phase does DNA replication occur?

• A. Telophase
• B. Metaphase
• C. S phase of interphase
• D. Prophase

Answer: (C)

Verified step by step guidance

1. Understand the phases of the cell cycle, which include interphase and mitosis. Interphase itself is divided into G1, S, and G2 phases.
2. Recall that DNA replication is the process of copying the entire genome to prepare for cell division, ensuring each daughter cell receives a complete set of chromosomes.
3. Identify that mitosis consists of phases such as prophase, metaphase, anaphase, and telophase, which are primarily involved in chromosome segregation, not DNA replication.
4. Recognize that DNA replication occurs during the S phase (Synthesis phase) of interphase, which precedes mitosis.
5. Conclude that among the options given, the S phase of interphase is the correct phase where DNA replication takes place.