Outline the events that occur during initiation of translation in E. coli.
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
11. Translation
Translation
Problem 7
Textbook Question
Assuming that each nucleotide in an mRNA is 0.34 nm long, how many triplet codes can simultaneously occupy the space in a ribosome that is 20 nm in diameter?
Verified step by step guidance1
Understand the problem: We need to find how many triplet codons (each consisting of 3 nucleotides) can fit within the length of the ribosome, which is given as 20 nm in diameter. Each nucleotide is 0.34 nm long, so the total length occupied by a triplet codon is 3 times 0.34 nm.
Calculate the length of one triplet codon by multiplying the length of a single nucleotide by 3: \$3 \times 0.34 \text{ nm}$.
Determine how many such triplet codons can fit into the 20 nm space by dividing the total length of the ribosome (20 nm) by the length of one triplet codon: \(\frac{20 \text{ nm}}{3 \times 0.34 \text{ nm}}\).
Interpret the result as the number of triplet codons that can simultaneously occupy the ribosome space. Since the number of codons must be a whole number, consider whether to round down to the nearest whole number.
Summarize the approach: by dividing the ribosome length by the length of one codon, you find the maximum number of codons that can fit simultaneously in the ribosome.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Structure and Length of mRNA Nucleotides
mRNA is composed of nucleotides arranged linearly, each approximately 0.34 nm in length. This measurement helps determine how much physical space a sequence of nucleotides occupies, which is essential for calculating how many codons fit within a given length.
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Triplet Codon Concept in Genetic Code
A triplet codon consists of three consecutive nucleotides in mRNA that encode a specific amino acid during protein synthesis. Understanding that codons are groups of three nucleotides is crucial for relating nucleotide length to the number of codons present.
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Physical Constraints of the Ribosome
The ribosome is a molecular machine with a defined size, here given as 20 nm in diameter. Knowing the ribosome's spatial dimensions allows us to estimate how many nucleotides or codons can physically fit inside its active site during translation.
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Ribosome Structure
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