10. Hypothesis Testing for Two Samples

The data below is taken from two random, independent samples. Calculate the margin of error for a 99% confidence interval for the difference in population proportions.

$x_1=87$, $x_2=68$

$n_1=120$, $n_2=115$

Denomination Effect A trial was conducted with 75 women in China given a 100-yuan bill, while another 75 women in China were given 100 yuan in the form of smaller bills (a 50-yuan bill plus two 20-yuan bills plus two 5-yuan bills). Among those given the single bill, 60 spent some or all of the money. Among those given the smaller bills, 68 spent some or all of the money (based on data from “The Denomination Effect,” by Raghubir and Srivastava, Journal of Consumer Research, Vol. 36). We want to use a 0.05 significance level to test the claim that when given a single large bill, a smaller proportion of women in China spend some or all of the money when compared to the proportion of women in China given the same amount in smaller bills.

a. Test the claim using a hypothesis test.

Denomination Effect A trial was conducted with 75 women in China given a 100-yuan bill, while another 75 women in China were given 100 yuan in the form of smaller bills (a 50-yuan bill plus two 20-yuan bills plus two 5-yuan bills). Among those given the single bill, 60 spent some or all of the money. Among those given the smaller bills, 68 spent some or all of the money (based on data from “The Denomination Effect,” by Raghubir and Srivastava, Journal of Consumer Research, Vol. 36). We want to use a 0.05 significance level to test the claim that when given a single large bill, a smaller proportion of women in China spend some or all of the money when compared to the proportion of women in China given the same amount in smaller bills.

c. If the significance level is changed to 0.01, does the conclusion change?

Clinical Trials of OxyContin OxyContin (oxycodone) is a drug used to treat pain, but it is well known for its addictiveness and danger. In a clinical trial, among subjects treated with OxyContin, 52 developed nausea and 175 did not develop nausea. Among other subjects given placebos, 5 developed nausea and 40 did not develop nausea (based on data from Purdue Pharma L.P.). Use a 0.05 significance level to test for a difference between the rates of nausea for those treated with OxyContin and those given a placebo.

c. Does nausea appear to be an adverse reaction resulting from OxyContin?

Color and Creativity Researchers from the University of British Columbia conducted trials to investigate the effects of color on creativity. Subjects with a red background were asked to think of creative uses for a brick; other subjects with a blue background were given the same task. Responses were scored by a panel of judges and results from scores of creativity are given below. Use a 0.05 significance level to test the claim that creative task scores have the same variation with a red background and a blue background.

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Color and Recall Researchers from the University of British Columbia conducted trials to investigate the effects of color on the accuracy of recall. Subjects were given tasks consisting of words displayed on a computer screen with background colors of red and blue. The subjects studied 36 words for 2 minutes, and then they were asked to recall as many of the words as they could after waiting 20 minutes. Results from scores on the word recall test are given below. Use a 0.05 significance level to test the claim that variation of scores is the same with the red background and blue background.

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Testing Effects of Alcohol Researchers conducted an experiment to test the effects of alcohol. Errors were recorded in a test of visual and motor skills for a treatment group of 22 people who drank ethanol and another group of 22 people given a placebo. The errors for the treatment group have a standard deviation of 2.20, and the errors for the placebo group have a standard deviation of 0.72 (based on data from “Effects of Alcohol Intoxication on Risk Taking, Strategy, and Error Rate in Visuomotor Performance,” by Streufert et al., Journal of Applied Psychology, Vol. 77, No. 4). Use a 0.05 significance level to test the claim that both groups have the same amount of variation among the errors.

Second-Hand Smoke Samples from Data Set 15 “Passive and Active Smoke” include cotinine levels measured in a group of smokers ( n = 40, x_bar = 172.48 ng/mL, 119.50 ng/mL ) and a group of nonsmokers not exposed to tobacco smoke ( n = 40, x_bar = 16.35 ng/mL, 62.53 ng/mL ). Cotinine is a metabolite of nicotine, meaning that when nicotine is absorbed by the body, cotinine is produced.

a. Use a 0.05 significance level to test the claim that the variation of cotinine in smokers is greater than the variation of cotinine in nonsmokers not exposed to tobacco smoke.

Second-Hand Smoke Samples from Data Set 15 “Passive and Active Smoke” include cotinine levels measured in a group of smokers ( n = 40, x_bar = 172.48 ng/mL, 119.50 ng/mL ) and a group of nonsmokers not exposed to tobacco smoke ( n = 40, x_bar = 16.35 ng/mL, 62.53 ng/mL ). Cotinine is a metabolite of nicotine, meaning that when nicotine is absorbed by the body, cotinine is produced.

b. The 40 cotinine measurements from the nonsmoking group consist of these values (all in ng/mL): 1, 1, 90, 244, 309, and 35 other values that are all 0. Does this sample appear to be from a normally distributed population? If not, how are the results from part (a) affected?

Denomination Effect A trial was conducted with 75 women in China given a 100-yuan bill, while another 75 women in China were given 100 yuan in the form of smaller bills (a 50-yuan bill plus two 20-yuan bills plus two 5-yuan bills). Among those given the single bill, 60 spent some or all of the money. Among those given the smaller bills, 68 spent some or all of the money (based on data from “The Denomination Effect,” by Raghubir and Srivastava, Journal of Consumer Research, Vol. 36). We want to use a 0.05 significance level to test the claim that when given a single large bill, a smaller proportion of women in China spend some or all of the money when compared to the proportion of women in China given the same amount in smaller bills.

b. Test the claim by constructing an appropriate confidence interval.

Clinical Trials of OxyContin OxyContin (oxycodone) is a drug used to treat pain, but it is well known for its addictiveness and danger. In a clinical trial, among subjects treated with OxyContin, 52 developed nausea and 175 did not develop nausea. Among other subjects given placebos, 5 developed nausea and 40 did not develop nausea (based on data from Purdue Pharma L.P.). Use a 0.05 significance level to test for a difference between the rates of nausea for those treated with OxyContin and those given a placebo.

a. Use a hypothesis test.

Cigarette Pack Warnings A study was conducted to find the effects of cigarette pack warnings that consisted of text or pictures. Among 1078 smokers given cigarette packs with text warnings, 366 tried to quit smoking. Among 1071 smokers given cigarette packs with warning pictures, 428 tried to quit smoking. (Results are based on data from “Effect of Pictorial Cigarette Pack Warnings on Changes in Smoking Behavior,” by Brewer et al., Journal of the American Medical Association.) Use a 0.01 significance level to test the claim that the proportion of smokers who tried to quit in the text warning group is less than the proportion in the picture warning group.

b. Test the claim by constructing an appropriate confidence interval.

Cigarette Pack Warnings A study was conducted to find the effects of cigarette pack warnings that consisted of text or pictures. Among 1078 smokers given cigarette packs with text warnings, 366 tried to quit smoking. Among 1071 smokers given cigarette packs with warning pictures, 428 tried to quit smoking. (Results are based on data from “Effect of Pictorial Cigarette Pack Warnings on Changes in Smoking Behavior,” by Brewer et al., Journal of the American Medical Association.) Use a 0.01 significance level to test the claim that the proportion of smokers who tried to quit in the text warning group is less than the proportion in the picture warning group.

a. Test the claim using a hypothesis test.

Can Dogs Detect Malaria? A study was conducted to determine whether dogs could detect malaria from socks worn by malaria patients and socks worn by patients without malaria. Among 175 socks worn by malaria patients, the dogs made correct identifications 123 times. Among 145 socks worn by patients without malaria, the dogs made correct identifications 131 times (based on data presented at an annual meeting of the American Society of Tropical Medicine, by principal investigator Steve Lindsay). Use a 0.05 significance level to test the claim of no difference between the two rates of correct responses.

a. Test the claim using a hypothesis test.

Overlap of Confidence Intervals In the article “On Judging the Significance of Differences by Examining the Overlap Between Confidence Intervals,” by Schenker and Gentleman (American Statistician, Vol. 55, No. 3), the authors consider sample data in this statement: “Independent simple random samples, each of size 200, have been drawn, and 112 people in the first sample have the attribute, whereas 88 people in the second sample have the attribute.”

c. Use a 0.05 significance level to test the claim that the two population proportions are equal. What do you conclude?