At which stage of mitosis are chromosomes usually photographed in the preparation of a karyotype?

• A. Telophase
• B. Prophase
• C. Metaphase
• D. Anaphase

Answer: (C)

Verified step by step guidance

1. Understand that a karyotype is a picture of chromosomes arranged in pairs, used to study chromosome number and structure.
2. Recall the stages of mitosis: prophase, metaphase, anaphase, and telophase, each with distinct chromosome arrangements.
3. Identify that chromosomes are most condensed and aligned at the cell's equatorial plate during metaphase, making them easiest to visualize clearly.
4. Recognize that in metaphase, chromosomes are highly condensed and lined up in the center, which allows for clear photographing and analysis.
5. Conclude that metaphase is the ideal stage for photographing chromosomes to prepare a karyotype because of their distinct, organized appearance.