Multiple Choice
In the context of DNA replication, what is the primary function of DNA polymerase?
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8. DNA Replication
Overview of DNA Replication
Multiple Choice
During DNA replication, what enzyme is responsible for “unzipping” the double helix by separating the two DNA strands at the replication fork?
A
Primase
B
DNA polymerase III
C
Ligase
D
Helicase
Verified step by step guidance1
Understand the process of DNA replication, which involves unwinding the double helix to allow each strand to be copied.
Identify the enzyme responsible for breaking the hydrogen bonds between complementary base pairs, effectively separating the two DNA strands.
Recall that this enzyme acts at the replication fork, creating two single-stranded templates for replication.
Recognize that Primase synthesizes RNA primers, DNA polymerase III adds nucleotides, and Ligase joins Okazaki fragments, so these are not responsible for unzipping.
Conclude that the enzyme Helicase is the one that 'unzips' the DNA by separating the strands at the replication fork.
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