17. Mutation, Repair, and Recombination
Types of Mutations
Problem 33d
Textbook Question
Textbook QuestionIn an experiment employing the methods of the Ames test, two strains of Salmonella are used. Strain A contains a base-substitution mutation, and Strain B contains a frameshift mutation. Four plates are prepared to test the mutagenicity of the compound ethyl methanesulfonate (EMS). Plate 1 is a control plate with Strain A and S9 extract but no EMS. Plate 2 is also a control plate and contains Strain B and S9 extract but no EMS. Plate 3 contains Strain A along with S9 extract and EMS, and Plate 4 contains Strain B, S9 extract, and EMS. Suppose the compound being tested was proflavin instead of EMS. Would this change the Ames test results? Explain why or why not.
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