In the context of types of mutations, how does a frameshift mutation most often affect the resulting protein?

• A. It substitutes one amino acid for another without changing the reading frame, usually affecting only a single amino acid.
• B. It duplicates an entire gene, increasing protein dosage but not changing the amino acid sequence of the original protein.
• C. It changes the reading frame so that many downstream codons are altered, often producing a drastically different protein and/or a premature stop codon.
• D. It removes an intron during RNA processing, preventing translation of the mRNA.

Answer: (C)