Transcription is similar to DNA replication in that:

• A. Both processes synthesize double-stranded DNA molecules.
• B. Both processes result in the production of identical daughter DNA molecules.
• C. Both processes use RNA polymerase as the main enzyme.
• D. Both processes require a DNA template strand.

Answer: (D)

Verified step by step guidance

1. Understand the processes involved: DNA replication produces a double-stranded DNA molecule by copying the entire DNA, while transcription produces a single-stranded RNA molecule from a DNA template.
2. Identify the main enzymes: DNA replication uses DNA polymerase to synthesize new DNA strands, whereas transcription uses RNA polymerase to synthesize RNA.
3. Recognize the product differences: DNA replication results in two identical double-stranded DNA molecules, but transcription results in an RNA molecule that is complementary to the DNA template strand.
4. Focus on the commonality: Both processes require a DNA template strand to guide the synthesis of a new nucleic acid strand, ensuring the correct sequence is produced.
5. Conclude that the key similarity is the use of a DNA template strand, which is essential for both DNA replication and transcription to occur accurately.