Describe the organization of the interphase nucleus. Include in your presentation a description of chromosome territories and interchromatin compartments.

Present an overview of the manner in which chromatin can be remodeled. Describe the manner in which these remodeling processes influence transcription.

List three types of alternative splicing patterns and how they lead to the production of different protein isoforms.

Consider the CT/CGRP example of alternative splicing shown in Figure 16.9. Which different types of alternative splicing patterns are represented?

Nonsense-mediated decay is an mRNA surveillance pathway that eliminates mRNAs with premature stop codons. How does the cell distinguish between normal mRNAs and those with a premature stop?