Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Dihybrid Cross
Problem 12b
Textbook Question
In Drosophila, gray body color is dominant to ebony body color, while long wings are dominant to vestigial wings. Assuming that the P₁ individuals are homozygous, work the following crosses through the F₂ generation, and determine the genotypic and phenotypic ratios for each generation.
gray, vestigial x ebony, long
Verified step by step guidance1
Identify the traits and their dominance relationships: gray body color (G) is dominant to ebony (g), and long wings (L) are dominant to vestigial wings (l). Since the P₁ individuals are homozygous, assign genotypes accordingly. For example, gray body with long wings would be GGLL, and ebony body with vestigial wings would be ggll.
Set up the P₁ cross using the homozygous parents: cross GGLL (gray, long) with ggll (ebony, vestigial). This will produce the F₁ generation, which will be heterozygous for both traits (GgLl).
Determine the phenotype and genotype of the F₁ generation: since both traits are dominant, all F₁ individuals will show gray body and long wings, and their genotype will be GgLl.
Set up the F₁ cross to produce the F₂ generation: cross two F₁ individuals (GgLl x GgLl). Use a dihybrid Punnett square to determine the possible genotypes and phenotypes of the F₂ offspring.
Calculate the genotypic and phenotypic ratios for the F₂ generation by analyzing the Punnett square results. The phenotypic ratio for two independently assorting dominant traits typically follows a 9:3:3:1 pattern (9 gray long, 3 gray vestigial, 3 ebony long, 1 ebony vestigial), and the genotypic ratio can be derived by counting all genotype combinations.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Mendelian Inheritance and Dominance
Mendelian inheritance explains how traits are passed from parents to offspring through dominant and recessive alleles. A dominant allele masks the expression of a recessive allele in heterozygotes, determining the phenotype. In this question, gray body and long wings are dominant traits, while ebony body and vestigial wings are recessive.
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Variations on Dominance
Genotypic and Phenotypic Ratios
Genotypic ratios describe the frequency of different allele combinations in offspring, while phenotypic ratios describe the frequency of observable traits. These ratios are predicted using Punnett squares, especially when crossing homozygous parents and analyzing subsequent generations like F1 and F2.
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Gamete Genotypes
Dihybrid Cross and Independent Assortment
A dihybrid cross involves two traits, each with two alleles, to study how they assort independently according to Mendel’s second law. This allows prediction of combined phenotypes and genotypes in offspring, such as body color and wing type in Drosophila, by analyzing the F1 and F2 generations.
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Related Practice
Textbook Question
Based on the preceding cross, what is the probability that an organism in the F₂ generation will have round seeds and green cotyledons and be true breeding?
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