During which phase of mitosis do centromeres divide, allowing sister chromatids to separate?

• A. Metaphase
• B. Anaphase
• C. Prophase
• D. Telophase

Answer: (B)

Verified step by step guidance

1. Recall the main phases of mitosis: Prophase, Metaphase, Anaphase, and Telophase, each with distinct events.
2. Understand that during Prophase, chromosomes condense and the mitotic spindle begins to form, but sister chromatids remain attached.
3. In Metaphase, chromosomes align at the metaphase plate, but the centromeres have not yet divided.
4. During Anaphase, the centromeres divide, allowing the sister chromatids to separate and move toward opposite poles of the cell.
5. Finally, in Telophase, the chromatids reach the poles and begin to decondense, and the nuclear envelope reforms.