During which phase of mitosis do sister chromatids separate and move toward opposite poles of the cell?

• A. Metaphase
• B. Anaphase
• C. Telophase
• D. Prophase

Answer: (B)

Verified step by step guidance

1. Recall the main phases of mitosis: Prophase, Metaphase, Anaphase, and Telophase, each with distinct events.
2. Understand that during Metaphase, chromosomes align at the cell's equatorial plate but sister chromatids remain attached.
3. Identify that the separation of sister chromatids occurs when the centromeres split, allowing chromatids to move to opposite poles.
4. Recognize that this separation and movement happen specifically during Anaphase.
5. Confirm that in Telophase, the chromatids have reached the poles and the cell begins to divide, completing mitosis.