During mitosis in a human cell, how many kinetochores are present at metaphase?

• A. 46
• B. 184
• C. 92
• D. 23

Answer: (C)

Verified step by step guidance

1. Recall that a human somatic cell has 46 chromosomes in total, which are present as pairs (diploid number).
2. Understand that during metaphase of mitosis, each chromosome consists of two sister chromatids joined at the centromere.
3. Each chromatid has one kinetochore, so the number of kinetochores equals the total number of chromatids.
4. Since each chromosome has 2 chromatids at metaphase, multiply the number of chromosomes by 2: \$46 \times 2$.
5. The result gives the total number of kinetochores present at metaphase in a human cell.