Go to the website http://www.ncbi.nlm.nih.gov/omim and enter 'Lynch syndrome' in the Search box at the top of the page. From the list of options given, select '#120435—Lynch Syndrome.' Use the information you retrieve to answer the following questions. There are two types of Lynch syndrome. What are they?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
19. Cancer Genetics
Overview of Cancer
Problem 15
Textbook Question
Mammography is an accurate screening technique for the early detection of breast cancer in humans. Because this technique uses X rays diagnostically, it has been highly controversial. Can you explain why? What reasons justify the use of X rays for such a medical screening technique?
Verified step by step guidance1
Understand that mammography uses X rays, which are a form of ionizing radiation capable of damaging DNA and potentially causing mutations that may lead to cancer.
Recognize the controversy arises because exposure to X rays, even at low doses, carries a risk of inducing cancer, creating a concern about the safety of repeated screenings.
Consider the risk-benefit analysis: while X rays have potential risks, mammography can detect breast cancer early, significantly improving treatment outcomes and survival rates.
Acknowledge that the justification for using X rays in mammography is based on the principle that the benefits of early cancer detection outweigh the relatively low risk of radiation-induced harm.
Note that modern mammography techniques use the lowest possible dose of X rays to minimize risk, and screening guidelines are designed to balance early detection benefits with minimizing unnecessary exposure.
Verified video answer for a similar problem:This video solution was recommended by our tutors as helpful for the problem above
Video duration:
1mPlay a video:
Was this helpful?
Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Ionizing Radiation and DNA Damage
X rays are a form of ionizing radiation that can penetrate tissues and cause damage to DNA by creating breaks or mutations. This damage can potentially lead to cancer development, which raises concerns about the safety of repeated exposure during diagnostic procedures like mammography.
Recommended video:
Guided course
DNA Proofreading
Risk-Benefit Analysis in Medical Screening
Medical screening techniques like mammography are evaluated by weighing the risks of radiation exposure against the benefits of early cancer detection. Early diagnosis can significantly improve treatment outcomes and survival rates, often justifying the controlled use of X rays despite their risks.
Recommended video:
Guided course
Step 2
Radiation Dose and Safety Measures
Mammography uses low doses of X rays optimized to minimize radiation exposure while maintaining image quality. Safety protocols and technological advances help reduce risks, making the procedure safer and more acceptable for routine breast cancer screening.
Recommended video:
Guided course
Mathematical Measurements
Watch next
Master Cancer Characteristics with a bite sized video explanation from Kylia
Start learningRelated Videos
Related Practice
Textbook Question
434
views
