How do we know that in humans the X chromosomes play no role in human sex determination, while the Y chromosome causes maleness and its absence causes femaleness?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
3. Extensions to Mendelian Inheritance
Sex Chromosome
Problem 4
Textbook Question
Contrast the XX/XY and XX/X0 modes of sex determination.
Verified step by step guidance1
Begin by defining the XX/XY sex determination system: in this system, females have two X chromosomes (XX) and males have one X and one Y chromosome (XY). The presence of the Y chromosome typically determines maleness due to the SRY gene.
Next, define the XX/X0 sex determination system: here, females have two X chromosomes (XX), but males have only one X chromosome and no second sex chromosome (X0, where '0' indicates the absence of a chromosome).
Explain how sex is determined in each system: in XX/XY, the presence or absence of the Y chromosome determines sex, while in XX/X0, sex is determined by the number of X chromosomes, with males having a single X and females having two.
Discuss the genetic and phenotypic consequences of these systems, such as how dosage compensation mechanisms might differ due to the presence or absence of the Y chromosome and how this affects gene expression.
Summarize the evolutionary and biological significance of these systems, noting that XX/XY is common in mammals, while XX/X0 is found in some insects like grasshoppers, highlighting differences in chromosome structure and inheritance patterns.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
XX/XY Sex Determination System
In the XX/XY system, typically found in mammals, females have two X chromosomes (XX) and males have one X and one Y chromosome (XY). The presence of the Y chromosome, specifically the SRY gene, triggers male development, making this system chromosomal and gene-driven.
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XX/X0 Sex Determination System
The XX/X0 system, common in some insects like grasshoppers, involves females with two X chromosomes (XX) and males with only one X chromosome (X0), where '0' indicates the absence of a second sex chromosome. Sex is determined by the number of X chromosomes rather than the presence of a Y chromosome.
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Mechanisms of Sex Determination
Sex determination mechanisms vary by species and involve genetic or chromosomal cues that direct sexual development. Understanding how the presence or absence of specific chromosomes or genes influences gonadal differentiation is key to contrasting different systems like XX/XY and XX/X0.
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