Which of the following represents the chromosomal segregation into gametes after a reciprocal translocation caused by adjacent-1 segregation? N=Normal chromosome T = Tanslocated chromosome

• A. (N2 T1) and (N1 T2)
• B. (N1 T1) and (N2 T2)
• C. (T1 T2) and (N1 N2)

Answer: (A)

Verified step by step guidance

1. Understand the concept of reciprocal translocation: This is a chromosomal abnormality caused by the exchange of segments between two non-homologous chromosomes. It can lead to different segregation patterns during meiosis.
2. Learn about adjacent-1 segregation: In this type of segregation, non-homologous centromeres go to the same pole during meiosis, resulting in gametes that have one normal and one translocated chromosome from each pair.
3. Identify the chromosomes involved: In the problem, N1 and N2 represent normal chromosomes, while T1 and T2 represent translocated chromosomes.
4. Apply the adjacent-1 segregation pattern: This pattern results in gametes that contain one normal chromosome and one translocated chromosome from each pair, leading to combinations like (N2 T1) and (N1 T2).
5. Compare the options: Evaluate the given options to determine which one matches the expected outcome of adjacent-1 segregation, which is (N2 T1) and (N1 T2).