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Multiple Choice
In the context of types of mutations, which type of mutation is most likely to result in an abnormal amino acid sequence downstream of the mutation site?
A
Silent (synonymous) mutation that does not change the encoded amino acid
B
Missense mutation that substitutes one amino acid for another but does not alter the reading frame
C
Frameshift mutation caused by an insertion or deletion not in multiples of three nucleotides
D
Mutation in an intron that is spliced out and therefore does not affect the coding sequence