siRNAs target a variety of different RNA transcripts for degradation.

• A. True
• B. False

Answer: (B)

Verified step by step guidance

1. Understand the role of siRNAs (small interfering RNAs) in the cell. They are involved in the RNA interference (RNAi) pathway, where they play a crucial role in gene silencing.
2. Recognize that siRNAs are typically 20-25 nucleotides long and are double-stranded RNA molecules.
3. Learn that siRNAs guide the RNA-induced silencing complex (RISC) to complementary mRNA molecules, leading to their degradation and preventing translation into proteins.
4. Clarify that siRNAs are highly specific to their target mRNA sequences. They do not target a variety of different RNA transcripts indiscriminately; instead, they are designed to match specific sequences.
5. Conclude that the statement 'siRNAs target a variety of different RNA transcripts for degradation' is false because siRNAs are sequence-specific and target specific mRNA sequences for degradation.