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1. Introduction to Genetics(0)

History of Genetics
(0)

Modern Genetics
(0)

Fundamentals of Genetics
(0)

2. Mendel's Laws of Inheritance(0)

Mendel's Experiments and Laws
(0)

Inheritance in Diploids and Haploids
(0)

Monohybrid Cross
(0)

Dihybrid Cross
(0)

Sex-Linked Genes
(0)

Probability and Genetics
(0)

Pedigrees
(0)

3. Extensions to Mendelian Inheritance(0)

Understanding Independent Assortment
(0)

Chi Square Analysis
(0)

Sex Chromosome
(0)

X-Inactivation
(0)

Overview of interacting Genes
(0)

Pleiotropy
(0)

Epistasis and Complementation
(0)

Variations of Dominance
(0)

Penetrance and Expressivity
(0)

Organelle DNA
(0)

Maternal Effect
(0)

4. Genetic Mapping and Linkage(0)

Mapping Overview
(0)

Crossing Over and Recombinants
(0)

Mapping Genes
(0)

Trihybrid Cross
(0)

Multiple Cross Overs and Interference
(0)

Chi Square and Linkage
(0)

Mapping with Markers
(0)

Positional Cloning
(0)

5. Genetics of Bacteria and Viruses(0)

Working with Microorganisms
(0)

Bacterial Conjugation
(0)

Bacterial Transformation
(0)

Bacteriophage Genetics
(0)

Transduction
(0)

6. Chromosomal Variation(0)

Chromosomal Mutations: Aberrant Euploidy
(0)

Chromosomal Mutations: Aneuploidy
(0)

Chromosomal Rearrangements: Overview
(0)

Chromosomal Rearrangements: Deletions
(0)

Chromosomal Rearrangements: Duplications
(0)

Chromosomal Rearrangements: Inversions
(0)

Chromosomal Rearrangements: Translocations
(0)

7. DNA and Chromosome Structure(0)

DNA as the Genetic Material
(0)

DNA Structure
(0)

Alternative DNA Forms
(0)

RNA
(0)

Bacterial and Viral Chromosome Structure
(0)

Eukaryotic Chromosome Structure
(0)

8. DNA Replication(0)

Semiconservative Replication
(0)

Overview of DNA Replication
(0)

Telomeres and Telomerase
(0)

Recombination
(0)

9. Mitosis and Meiosis(0)

Mitosis
(0)

Meiosis
(0)

Development of Animal Gametes
(0)

Development of Plant Gametes
(0)

10. Transcription(0)

Overview of Transcription
(0)

Transcription in Prokaryotes
(0)

Transcription in Eukaryotes
(0)

RNA Modification and Processing
(0)

RNA Interference
(0)

11. Translation(0)

The Genetic Code
(0)

Transfer RNA
(0)

Ribosomal Structure
(0)

Translation
(0)

Proteins
(0)

12. Gene Regulation in Prokaryotes(0)

Lac Operon
(0)

Tryptophan Operon and Attenuation
(0)

Lambda Bacteriophage and Life Cycle Regulation
(0)

Arabinose Operon
(0)

Riboswitches
(0)

13. Gene Regulation in Eukaryotes(0)

Overview of Eukaryotic Gene Regulation
(0)

GAL Regulation
(0)

Epigenetics, Chromatin Modifications, and Regulation
(0)

Post Translational Modifications
(0)

14. Genetic Control of Development(0)

Studying the Genetics of Development
(0)

Developmental Patterning Genes
(0)

Early Developmental Steps
(0)

15. Genomes and Genomics(0)

Overview of Genomics
(0)

Sequencing the Genome
(0)

Genomic Variation
(0)

Bioinformatics
(0)

Comparative Genomics
(0)

Genomics and Human Medicine
(0)

Functional Genomics
(0)

Proteomics
(0)

16. Transposable Elements(0)

Discovery of Transposable Elements
(0)

Transposable Elements in Prokaryotes
(0)

Transposable Elements in Eukaryotes
(0)

Regulation of Transposable Elements
(0)

17. Mutation, Repair, and Recombination(0)

Types of Mutations
(0)

Spontaneous Mutations
(0)

Induced Mutations
(0)

DNA Repair
(0)

18. Molecular Genetic Tools(0)

Genetic Cloning
(0)

Methods for Analyzing DNA
(0)

19. Cancer Genetics(0)

Overview of Cancer
(0)

Cancer Mutations
(0)

20. Quantitative Genetics(0)

Mathematical Measurements
(0)

Traits and Variance
(0)

Analyzing Trait Variance
(0)

Heritability
(0)

QTL Mapping
(0)

21. Population Genetics(0)

Hardy Weinberg
(0)

Allelic Frequency Changes
(0)

22. Evolutionary Genetics(0)

Overview of Evolution
(0)

Speciation
(0)

Phylogenetic Trees
(0)

17. Mutation, Repair, and Recombination

DNA Repair

17. Mutation, Repair, and Recombination

DNA Repair: Videos & Practice Problems

Video Lessons Practice Worksheet

Back to all problems

24 of 0

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Problem 24Multiple Choice

CpG dinucleotides are a pair of nucleotides consisting of a cytosine followed by a guanine, where the C and G are connected by a phosphate group. CpG islands are typically unmethylated in normal cells, and their methylation status is associated with gene expression. Which statement provides the best explanation for why methylated CpG dinucleotides undergo deamination 10 times faster than unmethylated CpG dinucleotides?

Methylated CpG dinucleotides are more stable than unmethylated CpG dinucleotides, which makes them more prone to deamination.

The presence of the methyl group in the 5 position of the cytosine ring makes the C-N bond between the amino group and the ring more susceptible to hydrolysis, which promotes deamination.

Methylated CpG dinucleotides are less accessible to DNA repair mechanisms than unmethylated CpG dinucleotides, which increases their likelihood of deamination.

Deamination of CpG dinucleotides occurs randomly and is not affected by their methylation status.

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