An upstream activating sequence (UAS) is a cis-acting regulatory ...

13. Gene Regulation in Eukaryotes

GAL Regulation

13. Gene Regulation in Eukaryotes

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The transactivators bind to the target at the UAS recruiting a mediator.

The transactivators bind to the target at the UAS recruiting a mediator yet the initiation of transcription is stopped.

The transactivators cannot bind with the UAS element and the initiation of transcription is stopped.

The transactivators cannot bind with the UAS element yet the initiation of transcription is not stopped.

An upstream activating sequence (UAS) is a cis-acting regulatory sequence that increases the expression of a neighboring gene by acting as a binding site for transactivators. The deletion of the UAS gene element leads to: