Ras, a small G protein located at the plasma membrane, is often mutated in different types of cancer. Ras normally signals to a cell that it should divide. Cancer cells divide uncontrollably. Which of the following changes to Ras could explain uncontrolled division in a cancer cell that has mutated Ras present?
A mutation that leads to Ras being sent to the endomembrane system
A mutation that means Ras cannot bind to GTP
A mutation that means GDP is constantly bound to Ras
A mutation in which Ras cannot bind to its GPCR
A mutation that means Ras cannot hydrolyze GTP to GDP