20. Adaptive Immunity

Where do T cells undergo central tolerance selection?

The most important function of peripheral tolerance is to:

What is immunological tolerance?

Which of the following is NOT a consequence of the immune system lacking an immune tolerance?

Summarize the causes of immunodeficiencies. What is the effect of an immunodeficiency?

Explain what happens when a person develops a contact sensitivity to the poison oak plant.

a. What causes the observed symptoms?

b. How did the sensitivity develop?

c. How might this person be desensitized to poison oak?

Differentiate the three types of autoimmune diseases. Name an example of each type.

In which of the following scenarios would administering immunoglobulins be useful? Select all that apply. (NCLEX/HESI/TEAS)

a. To neutralize a toxin

b. To aid a patient who is immune compromised

c. After venom exposure

d. To block IgM from crossing the placenta

e. To protect a premature infant from respiratory syncytial virus

Where do T cells undergo self-tolerance selection?

When a surgeon conducts a cardiac bypass operation by transplanting a piece of vein from a patient’s leg to the same patient’s heart, this is a(n):

a. Rejected graft

b. Autograft

c. Allograft

d. Type IV hypersensitivity

e. Cardiograft

Indicate whether each statement is true or false. If the statement is false, change the underlined word or phrase to make the statement true.

______Graft-versus-host disease can follow a bone marrow isograft.

Contrast autografts, isografts, allografts, and xenografts.

Compare and contrast the functions of four classes of immunosuppressive drugs.

Label the four types of grafts on the accompanying figure.