19. Innate Immunity

The initiation pathways of the complement system result in the formation of C3 convertase and the cleaving of C3 into C3a & C3b. Where does C3b in the alternative pathway come from if C3 convertase has not yet been created?

The alternative pathway resulting in the formation of C3 convertase and the splitting of C3 into C3a and C3b. C3a triggers the inflammatory response. What is the function of C3b created by the alternative pathway?

Which of the following choices would not be able to stimulate the lectin pathway of the complement system?

Which of the following is not a mechanism that triggers the complement system?

If the following are placed in the order of occurrence, which would be the third step?

a. activation of C5 through C9

b. cell lysis

c. antigen–antibody reaction

d. activation of C3

e. activation of C2 through C4

The ____________ cascade of complement activation is initiated by antibodies. In contrast, the ____________ cascade is activated by a direct interaction with complement proteins, and the ____________ cascade is activated by MBL associating with a pathogen.

The alternative complement activation pathway involves:

a. Factors B, D, and P

b. The cleavage of C5 to form C9

c. Binding to mannose sugar

d. Recognition of antigens bound to specific antibodies