During which phase of mitosis are sister chromatids separated and pulled to opposite poles?

• A. Anaphase
• B. Prophase
• C. Metaphase
• D. Telophase

Answer: (A)

Verified step by step guidance

1. Understand the process of mitosis, which is the division of a single cell into two genetically identical daughter cells. Mitosis consists of several phases: prophase, metaphase, anaphase, and telophase.
2. Recall that sister chromatids are identical copies of a chromosome connected by a centromere. They are crucial for ensuring that each daughter cell receives the correct genetic information.
3. Identify the role of each mitotic phase: Prophase involves the condensation of chromatin into visible chromosomes and the formation of the mitotic spindle. Metaphase is characterized by the alignment of chromosomes along the metaphase plate.
4. Focus on anaphase, where the sister chromatids are separated. During this phase, the centromeres split, and the spindle fibers pull the chromatids apart to opposite poles of the cell.
5. Recognize that telophase is the final phase of mitosis, where the separated chromatids reach the poles, and the cell begins to divide, forming two new nuclei.