During which phase of mitosis would an error in chromosome alignment most likely occur?

• A. Metaphase
• B. Telophase
• C. Prophase
• D. Anaphase

Answer: (A)

Verified step by step guidance

1. Understand the phases of mitosis: Mitosis is divided into several phases: prophase, metaphase, anaphase, and telophase. Each phase has distinct events that occur in the cell.
2. Identify the key event in each phase: In prophase, chromosomes condense and the mitotic spindle begins to form. In metaphase, chromosomes align at the metaphase plate. In anaphase, sister chromatids are pulled apart to opposite poles. In telophase, the cell begins to divide, and the nuclear envelope re-forms.
3. Focus on chromosome alignment: Chromosome alignment is a critical event that occurs during metaphase. This is when chromosomes line up at the cell's equatorial plane, known as the metaphase plate.
4. Consider where errors in alignment could occur: Since chromosome alignment is a key event of metaphase, errors in alignment are most likely to occur during this phase.
5. Conclude with the phase where alignment errors are most likely: Based on the understanding of mitosis phases, errors in chromosome alignment would most likely occur during metaphase.