The function(s) of basophils is(are) ______.

• A. release histamine during inflammatory responses
• B. present antigens to T cells
• C. produce antibodies against pathogens
• D. phagocytose bacteria and cellular debris

Answer: (A)

Verified step by step guidance

1. Understand the role of basophils in the immune system. Basophils are a type of white blood cell involved in the body's defense mechanisms, particularly in allergic and inflammatory responses.
2. Recall that basophils release histamine, a chemical that plays a key role in inflammation and allergic reactions. Histamine causes blood vessels to dilate and become more permeable, allowing immune cells to access the affected area.
3. Differentiate basophils from other immune cells. For example, basophils do not phagocytose bacteria and debris (a function of macrophages and neutrophils) or produce antibodies (a function of B cells).
4. Note that basophils are not primarily involved in presenting antigens to T cells. This function is typically performed by antigen-presenting cells like dendritic cells and macrophages.
5. Conclude that the primary function of basophils is to release histamine during inflammatory responses, which helps mediate the body's reaction to allergens and injury.